An absence of sub-strain variation over a short period was seen in sick patients, which may signal impending gut dysbiosis. Casey D. Morrow, Ph.D.Casey D. Morrow, Ph.D., and colleagues at the University of Alabama at Birmingham previously developed a microbiome ‘fingerprint’ method called WSS that identifies single strains of particular gut bacteria, through analysis of metagenomics data from fecal samples. They have shown that particular strains in adults tend to remain stable over time, unless perturbed by events like antibiotics or obesity surgery.
A refined microbiome ‘fingerprint’ method tracks sub-strain variants of a single gut microbe strain
